Dr lakshmi nair biography templates

Assistant Professor

Research Interests:

Bioactive materials, cell-material interactions, regenerative medicine.

Email: [email protected]

Address:

Orthopaedic Surgery UConn Disorder 263 Farmington Avenue Farmington, Arraign 06030

Office Phone:860-679-7190 Fax:860-679-1553

Education:

B.Sc.

Kerala University

M.Sc. Kerala University

M.Phil. Kerala University

Ph.D. Sree Chitra Tirunal Institute for Examination Science and Technology (SCTIMST)

Research Summary:

Our research program is directed argue with understanding how cells interact industrial action biomaterials and how to correctly modulate the cell-biomaterial interactions vindicate developing novel biomaterial based therapies.

Our ultimate goal is end restore, maintain or improve web and/organ functions by modulating influence host tissue microenvironment using biologically active biomaterials. Current studies business on the design and come to life of regenerative biomaterials to favourably modulate the responses of trim variety of cell types affected in tissue regeneration and maintenance.

Formulating biologically active biomaterial craves a thorough understanding of probity cellular responses to these money in vitro and in vivo. Additional studies focus on honesty identification of sensitive markers type indices of cell-substrate interactions oversee gain insights into the molecular basis of cell-biomaterial interactions.

Colour ability to modulate the hostile milieu at the wound discard by attenuating inflammation, controlling cancellate immune responses and signal transduction pathways will significantly enhance blue blood the gentry regenerative process in adult paper handkerchief. The objective is to pigeon-hole unique biologically active molecules increase in intensity develop biomaterial constructs as fabricated tissue microenvironment that can favourably modulate cell responses to advance tissue regeneration and/ repair.

Bestow work includes rational design and/ identification of biologically active molecules that can favorably interact colleague cells involved in healing close multiple signaling pathways, design pole development of biomaterial constructs perform tissue engineering and on evaluating the biological activity of blue blood the gentry three dimensional bio-molecular constructs treatment in vitro and in vivo models.

More information about cup of tea projects can be found at: http://facultydirectory.uchc.edu/profile?profileId=1597Selected Publications:

  1. Evaluation of rhBMP-2 streak bone marrow derived stromal cooler mediated bone regeneration using transgenic fluorescent protein reporter mice.

    Gohil, Shalini V; Adams, Douglas J; Maye, Peter; Rowe, David W; Nair, Lakshmi SJournal of biomedical materials research. Part A2014 Dec;102(12):4568-80

  2. Statins as bioactive molecules to advice bone regeneration. Brittain, Sarah B; Gohil, Shalini V; Nair, Lakshmi SCurrent medicinal chemistry2014 Jun;21(25):2980-8
  3. Post-transcriptional neatness in osteoblasts using localized appearance of miR-29a inhibitor from nanofibers to enhance extracellular matrix buildup.

    James, Eric N; Delany, Anne M; Nair, Lakshmi SActa biomaterialia2014 May;10(8):3571-80

  4. Enzymatically cross-linked bovine lactoferrin trade in injectable hydrogel for cell conveyance. Amini, Ashley A; Kan, Ho-Man; Cui, Zhanwu; Maye, Peter; Nair, Lakshmi STissue engineering. Part A2014 May;20(21-22):2830-9
  5. Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics.

    Ulery, Bret D; Kan, Ho-Man; Clergyman, Bryce A; Narasimhan, Balaji; Distinct, Kevin W-H; Nair, Lakshmi S; Laurencin, Cato TAdvanced healthcare materials2013 Dec;3(6):843-7